Induction of Dickkopf-1, a Negative Modulator of the Wnt Pathway, Is Required for the Development of Ischemic Neuronal Death

Expression of Dickkopf-1 (Dkk-1), a secreted protein that negatively modulates the Wnt pathway, was induced in the hippocampus of gerbils and rats subjected to transient global cerebral ischemia as well as in cultured cortical neurons challenged with an excitotoxic pulse. In ischemic animals, the te...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Neurosci
Main Authors: Cappuccio, Irene, Calderone, Agata, Busceti, Carla L., Biagioni, Francesca, Pontarelli, Fabrizio, Bruno, Valeria, Storto, Marianna, Terstappen, Georg T., Gaviraghi, Giovanni, Fornai, Francesco, Battaglia, Giuseppe, Melchiorri, Daniela, Zukin, Suzanne, Nicoletti, Ferdinando, Caricasole, Andrea
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2005
נושאים:
Neurobiology of Disease
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725177/
https://ncbi.nlm.nih.gov/pubmed/15758175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5230-04.2005
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