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Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage

The identification of mechanisms that mediate stress-induced hippocampal damage may shed new light into the pathophysiology of depressive disorders and provide new targets for therapeutic intervention. We focused on the secreted glycoprotein Dickkopf-1 (Dkk-1), an inhibitor of the canonical Wnt path...

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Autori principali: Matrisciano, Francesco, Busceti, Carla L., Bucci, Domenico, Orlando, Rosamaria, Caruso, Alessandra, Molinaro, Gemma, Cappuccio, Irene, Riozzi, Barbara, Gradini, Roberto, Motolese, Marta, Caraci, Filippo, Copani, Agata, Scaccianoce, Sergio, Melchiorri, Daniela, Bruno, Valeria, Battaglia, Giuseppe, Nicoletti, Ferdinando
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029367/
https://ncbi.nlm.nih.gov/pubmed/21304589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016447
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