Activation of Protease-Activated Receptor-1 Triggers Astrogliosis after Brain Injury

We have studied the involvement of the thrombin receptor [protease-activated receptor-1 (PAR-1)] in astrogliosis, because extravasation of PAR-1 activators, such as thrombin, into brain parenchyma can occur after blood-brain barrier breakdown in a number of CNS disorders. PAR1(-/-) animals show a re...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nicole, Olivier, Goldshmidt, Anna, Hamill, Cecily E., Sorensen, Scott D., Sastre, Aristide, Lyuboslavsky, Polina, Hepler, John R., McKeon, Robert J., Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725104/
https://ncbi.nlm.nih.gov/pubmed/15858058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5200-04.2005
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