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Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function

Protease-activated receptor 1 (PAR1) is a G-protein coupled receptor that is expressed throughout the central nervous system. PAR1 activation by brain-derived as well as blood-derived proteases has been shown to have variable and complex effects in a variety of animal models of neuronal injury and i...

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Hlavní autoři: Hamill, Cecily E., Mannaioni, Guido, Lyuboslavsky, Polina, Sastre, Aristide A., Traynelis, Stephen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679858/
https://ncbi.nlm.nih.gov/pubmed/19416668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.01.023
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