α-Synuclein Phosphorylation Enhances Eosinophilic Cytoplasmic Inclusion Formation in SH-SY5Y Cells

Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of dopaminergic neurons and the presence of Lewy bodies. Previous reports have shown that α-synuclein deposited in brain tissue from individuals with synucleinopathy is extensively phosphorylated at Ser-129...

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Publicado en:J Neurosci
Autores principales: Smith, Wanli W., Margolis, Russell L., Li, Xiaojie, Troncoso, Juan C., Lee, Michael K., Dawson, Valina L., Dawson, Ted M., Iwatsubo, Takashi, Ross, Christopher A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Neurobiology of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724982/
https://ncbi.nlm.nih.gov/pubmed/15944382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0482-05.2005
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