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Thrombin-Induced Oxidative Stress Contributes to the Death of Hippocampal Neurons In Vivo: Role of Microglial NADPH Oxidase

The present study investigated whether thrombin, a potent microglial activator, can induce reactive oxygen species (ROS) generation through activation of microglial NADPH oxidase and if this may contribute to oxidative damage and consequent neurodegeneration. Seven days after intrahippocampal inject...

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Pubblicato in:J Neurosci
Autori principali: Choi, Sang-Ho, Lee, Da Yong, Kim, Seung Up, Jin, Byung Kwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724962/
https://ncbi.nlm.nih.gov/pubmed/15843610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4306-04.2005
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