Microglial Toll-like Receptor 2 Contributes to Kainic Acid-induced Glial Activation and Hippocampal Neuronal Cell Death

Recent studies indicate that Toll-like receptors (TLRs), originally identified as infectious agent receptors, also mediate sterile inflammatory responses during tissue damage. In this study, we investigated the role of TLR2 in excitotoxic hippocampal cell death using TLR2 knock-out (KO) mice. TLR2 e...

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書誌詳細
主要な著者: Hong, Jinpyo, Cho, Ik-Hyun, Il Kwak, Kyung, Suh, Eun Cheng, Seo, Jinsoo, Min, Hyun Jung, Choi, Se-Young, Kim, Chong-Hyun, Park, Seung Hwa, Jo, Eun-Kyeong, Lee, Soojin, Lee, Kyung Eun, Lee, Sung Joong
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
Neurobiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998094/
https://ncbi.nlm.nih.gov/pubmed/20923777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132522
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