Microglial Toll-like Receptor 2 Contributes to Kainic Acid-induced Glial Activation and Hippocampal Neuronal Cell Death

Recent studies indicate that Toll-like receptors (TLRs), originally identified as infectious agent receptors, also mediate sterile inflammatory responses during tissue damage. In this study, we investigated the role of TLR2 in excitotoxic hippocampal cell death using TLR2 knock-out (KO) mice. TLR2 e...

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Hlavní autoři: Hong, Jinpyo, Cho, Ik-Hyun, Il Kwak, Kyung, Suh, Eun Cheng, Seo, Jinsoo, Min, Hyun Jung, Choi, Se-Young, Kim, Chong-Hyun, Park, Seung Hwa, Jo, Eun-Kyeong, Lee, Soojin, Lee, Kyung Eun, Lee, Sung Joong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998094/
https://ncbi.nlm.nih.gov/pubmed/20923777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132522
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