Microglial Toll-like Receptor 2 Contributes to Kainic Acid-induced Glial Activation and Hippocampal Neuronal Cell Death

Recent studies indicate that Toll-like receptors (TLRs), originally identified as infectious agent receptors, also mediate sterile inflammatory responses during tissue damage. In this study, we investigated the role of TLR2 in excitotoxic hippocampal cell death using TLR2 knock-out (KO) mice. TLR2 e...

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Main Authors: Hong, Jinpyo, Cho, Ik-Hyun, Il Kwak, Kyung, Suh, Eun Cheng, Seo, Jinsoo, Min, Hyun Jung, Choi, Se-Young, Kim, Chong-Hyun, Park, Seung Hwa, Jo, Eun-Kyeong, Lee, Soojin, Lee, Kyung Eun, Lee, Sung Joong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998094/
https://ncbi.nlm.nih.gov/pubmed/20923777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132522
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