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A GIT1/PIX/Rac/PAK Signaling Module Regulates Spine Morphogenesis and Synapse Formation through MLC

Three of seven recently identified genes mutated in nonsyndromic mental retardation are involved in Rho family signaling. Two of the gene products, α-p-21-activated kinase (PAK) interacting exchange factor (αPIX) and PAK3, form a complex with the synaptic adaptor protein G-protein-coupled receptor k...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhang, Huaye, Webb, Donna J., Asmussen, Hannelore, Niu, Shuang, Horwitz, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724907/
https://ncbi.nlm.nih.gov/pubmed/15800193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3553-04.2005
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