A GIT1/PIX/Rac/PAK Signaling Module Regulates Spine Morphogenesis and Synapse Formation through MLC

Three of seven recently identified genes mutated in nonsyndromic mental retardation are involved in Rho family signaling. Two of the gene products, α-p-21-activated kinase (PAK) interacting exchange factor (αPIX) and PAK3, form a complex with the synaptic adaptor protein G-protein-coupled receptor k...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Zhang, Huaye, Webb, Donna J., Asmussen, Hannelore, Niu, Shuang, Horwitz, Alan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724907/
https://ncbi.nlm.nih.gov/pubmed/15800193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3553-04.2005
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