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Neurodegenerative Illness in Transgenic Mice Expressing a Transmembrane Form of the Prion Protein

Although PrP(Sc) is thought to be the infectious form of the prion protein, it may not be the form that is responsible for neuronal cell death in prion diseases. (Ctm)PrP is a transmembrane version of the prion protein that has been proposed to be a neurotoxic intermediate underlying prion-induced p...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Stewart, Richard S., Piccardo, Pedro, Ghetti, Bernardino, Harris, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724892/
https://ncbi.nlm.nih.gov/pubmed/15800202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0105-05.2005
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