Molecular Determinants of KCNQ (K(v)7) K(+) Channel Sensitivity to the Anticonvulsant Retigabine

Epilepsy is caused by an electrical hyperexcitability in the CNS. Because K(+) channels are critical for establishing and stabilizing the resting potential of neurons, a loss of K(+) channels could support neuronal hyperexcitability. Indeed, benign familial neonatal convulsions, an autosomal dominan...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Schenzer, Anne, Friedrich, Thomas, Pusch, Michael, Saftig, Paul, Jentsch, Thomas J., Grötzinger, Joachim, Schwake, Michael
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2005
Teme:
Cellular/Molecular
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724866/
https://ncbi.nlm.nih.gov/pubmed/15901787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0128-05.2005
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