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A carboxy-terminal domain determines the subunit specificity of KCNQ K(+) channel assembly
Mutations in KCNQ K(+) channel genes underlie several human pathologies. KCNQ α-subunits form either homotetramers or hetero-oligomers with a restricted subset of other KCNQ α-subunits or with KCNE β-subunits. KCNQ1 assembles with KCNE β-subunits but not with other KCNQ α-subunits. By contrast, KCNQ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315815/ https://ncbi.nlm.nih.gov/pubmed/12524525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor715 |
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