Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats

BACKGROUND: Temporomandibular disorders (TMDs) are characterized by persistent orofacial pain and have diverse etiologic factors that are not well understood. It is thought that central sensitization leads to neuronal hyperexcitability and contributes to hyperalgesia and spontaneous pain. Nonsteroid...

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Detalhes bibliográficos
Main Authors: Xu, Wen, Wu, Yuwei, Bi, Yeping, Tan, Lei, Gan, Yehua, Wang, KeWei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936374/
https://ncbi.nlm.nih.gov/pubmed/20796319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-49
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