Cyclin-Dependent Kinase 5 Mediates Neurotoxin-Induced Degradation of the Transcription Factor Myocyte Enhancer Factor 2

Regulation of the process of neuronal death plays a central role both during development of the CNS and in adult brain. The transcription factor myocyte enhancer factor 2 (MEF2) plays a critical role in neuronal survival. Cyclin-dependent kinase 5 (Cdk5) mediates neurotoxic effects by phosphorylatin...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tang, Xiaoli, Wang, Xuemin, Gong, Xiaoming, Tong, Ming, Park, David, Xia, Zhengui, Mao, Zixu
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724765/
https://ncbi.nlm.nih.gov/pubmed/15888658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1331-05.2005
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