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IRSp53 coordinates AMPK and 14-3-3 signaling to regulate filopodia dynamics and directed cell migration

Filopodia are actin-filled membrane protrusions that play essential roles in cell motility and cell–cell communication and act as precursors of dendritic spines. IRSp53 is an essential regulator of filopodia formation, which couples Rho-GTPase signaling to actin cytoskeleton and membrane remodeling....

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Kast, David J., Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724608/
https://ncbi.nlm.nih.gov/pubmed/30893014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-09-0600
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