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Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination

The vertebrate lens provides an excellent model with which to study the mechanisms required for epithelial invagination. In the mouse, the lens forms from the head surface ectoderm. A domain of ectoderm first thickens to form the lens placode and then invaginates to form the lens pit. The epithelium...

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Détails bibliographiques
Auteurs principaux: Chauhan, Bharesh K., Disanza, Andrea, Choi, Sue-Yeon, Faber, Sonya C., Lou, Ming, Beggs, Hilary E., Scita, Giorgio, Zheng, Yi, Lang, Richard A.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761112/
https://ncbi.nlm.nih.gov/pubmed/19820184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.042242
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