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T-Cell Receptor Cognate Target Prediction Based on Paired α and β Chain Sequence and Structural CDR Loop Similarities

T-cell receptors (TCR) mediate immune responses recognizing peptides in complex with major histocompatibility complexes (pMHC) displayed on the surface of cells. Resolving the challenge of predicting the cognate pMHC target of a TCR would benefit many applications in the field of immunology, includi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lanzarotti, Esteban, Marcatili, Paolo, Nielsen, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724566/
https://ncbi.nlm.nih.gov/pubmed/31555288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02080
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