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T-Cell Receptor Cognate Target Prediction Based on Paired α and β Chain Sequence and Structural CDR Loop Similarities

T-cell receptors (TCR) mediate immune responses recognizing peptides in complex with major histocompatibility complexes (pMHC) displayed on the surface of cells. Resolving the challenge of predicting the cognate pMHC target of a TCR would benefit many applications in the field of immunology, includi...

詳細記述

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書誌詳細
出版年:Front Immunol
主要な著者: Lanzarotti, Esteban, Marcatili, Paolo, Nielsen, Morten
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724566/
https://ncbi.nlm.nih.gov/pubmed/31555288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02080
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