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Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex

Autophagy is a conserved eukaryotic pathway critical for cellular adaptation to changes in nutrition levels and stress. The class III phosphatidylinositol (PI)3-kinase complexes I and II (PI3KC3-C1 and -C2) are essential for autophagosome initiation and maturation, respectively, from highly curved v...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Brier, Livia W., Ge, Liang, Stjepanovic, Goran, Thelen, Ashley M., Hurley, James H., Schekman, Randy
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724508/
https://ncbi.nlm.nih.gov/pubmed/30811270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-11-0743
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