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High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status

BACKGROUND: Vulvar squamous cell carcinoma (VSCC) has been suggested to consist of three subtypes; HPV-positive, HPV-negative mutated TP53 or HPV-negative TP53 wildtype, with different clinical courses. To analyze the immune infiltrate in these molecular subtypes and its impact on clinical outcome,...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Kortekaas, Kim E., Santegoets, Saskia J., Abdulrahman, Ziena, van Ham, Vanessa J., van der Tol, Marij, Ehsan, Ilina, van Doorn, Helena C., Bosse, Tjalling, van Poelgeest, Mariëtte I. E., van der Burg, Sjoerd H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724316/
https://ncbi.nlm.nih.gov/pubmed/31481117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0712-z
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