Association of Change in N-Terminal Pro–B-Type Natriuretic Peptide Following Initiation of Sacubitril-Valsartan Treatment With Cardiac Structure and Function in Patients With Heart Failure With Reduced Ejection Fraction

IMPORTANCE: In patients with heart failure and reduced ejection fraction (HFrEF), treatment with sacubitril-valsartan reduces N-terminal pro–b-type natriuretic peptide (NT-proBNP) concentrations. The effect of sacubitril-valsartan on cardiac remodeling is uncertain. OBJECTIVE: To determine whether N...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Januzzi, James L., Prescott, Margaret F., Butler, Javed, Felker, G. Michael, Maisel, Alan S., McCague, Kevin, Camacho, Alexander, Piña, Ileana L., Rocha, Ricardo A., Shah, Amil M., Williamson, Kristin M., Solomon, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724151/
https://ncbi.nlm.nih.gov/pubmed/31475295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.12821
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