Association of Change in N-Terminal Pro–B-Type Natriuretic Peptide Following Initiation of Sacubitril-Valsartan Treatment With Cardiac Structure and Function in Patients With Heart Failure With Reduced Ejection Fraction

IMPORTANCE: In patients with heart failure and reduced ejection fraction (HFrEF), treatment with sacubitril-valsartan reduces N-terminal pro–b-type natriuretic peptide (NT-proBNP) concentrations. The effect of sacubitril-valsartan on cardiac remodeling is uncertain. OBJECTIVE: To determine whether N...

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Vydáno v:JAMA
Hlavní autoři: Januzzi, James L., Prescott, Margaret F., Butler, Javed, Felker, G. Michael, Maisel, Alan S., McCague, Kevin, Camacho, Alexander, Piña, Ileana L., Rocha, Ricardo A., Shah, Amil M., Williamson, Kristin M., Solomon, Scott D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724151/
https://ncbi.nlm.nih.gov/pubmed/31475295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.12821
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