Effect of Sacubitril-Valsartan vs Enalapril on Aortic Stiffness in Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial

IMPORTANCE: Compared with enalapril, sacubitril-valsartan reduces cardiovascular mortality and heart failure hospitalization in patients with heart failure and reduced ejection fraction (HFrEF). These benefits may be related to effects on hemodynamics and cardiac remodeling. OBJECTIVE: To determine...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Desai, Akshay S., Solomon, Scott D., Shah, Amil M., Claggett, Brian L., Fang, James C., Izzo, Joseph, McCague, Kevin, Abbas, Cheryl A., Rocha, Ricardo, Mitchell, Gary F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749534/
https://ncbi.nlm.nih.gov/pubmed/31475296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.12843
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