Effect of Sacubitril-Valsartan vs Enalapril on Aortic Stiffness in Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial

IMPORTANCE: Compared with enalapril, sacubitril-valsartan reduces cardiovascular mortality and heart failure hospitalization in patients with heart failure and reduced ejection fraction (HFrEF). These benefits may be related to effects on hemodynamics and cardiac remodeling. OBJECTIVE: To determine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JAMA
Prif Awduron: Desai, Akshay S., Solomon, Scott D., Shah, Amil M., Claggett, Brian L., Fang, James C., Izzo, Joseph, McCague, Kevin, Abbas, Cheryl A., Rocha, Ricardo, Mitchell, Gary F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Medical Association 2019
Pynciau:
Original Investigation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749534/
https://ncbi.nlm.nih.gov/pubmed/31475296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.12843
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