Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

Radiolabelled antagonistic bombesin analogues are successfully used for targeting of gastrin-releasing peptide receptors (GRPR) that are overexpressed in prostate cancer. Internalization of antagonistic bombesin analogues is slow. We hypothesized that the use of a non-residualizing radioiodine label...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Oroujeni, Maryam, Abouzayed, Ayman, Lundmark, Fanny, Mitran, Bogdan, Orlova, Anna, Tolmachev, Vladimir, Rosenström, Ulrika
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724035/
https://ncbi.nlm.nih.gov/pubmed/31382362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11080380
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