Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Gastrin-releasing peptide receptor (GRPR) is overexpressed in the majority of prostate cancers. This study aimed to investigate the potential of (64)Cu (radionuclide for late time-point PET-imaging) for imaging of GRPR expression using NOTA-PEG(2)-RM26 and NODAGA-PEG(2)-RM26. Methods: NOTA/NODAGA-PE...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Baun, Christina, Mitran, Bogdan, Rinne, Sara S., Dam, Johan H., Olsen, Birgitte B., Tolmachev, Vladimir, Orlova, Anna, Thisgaard, Helge
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766840/
https://ncbi.nlm.nih.gov/pubmed/33352838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245993
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