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PARP Inhibitors in Prostate Cancer–the Preclinical Rationale and Current Clinical Development

Prostate cancer is globally the second most commonly diagnosed cancer type in men. Recent studies suggest that mutations in DNA repair genes are associated with aggressive forms of prostate cancer and castration resistance. Prostate cancer with DNA repair defects may be vulnerable to therapeutic tar...

詳細記述

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書誌詳細
出版年:Genes (Basel)
主要な著者: Virtanen, Verneri, Paunu, Kreetta, Ahlskog, Johanna K., Varnai, Reka, Sipeky, Csilla, Sundvall, Maria
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723995/
https://ncbi.nlm.nih.gov/pubmed/31357527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10080565
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