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PARP Inhibitors: Science and Current Clinical Development
PURPOSE OF REVIEW: PARP inhibitors are a promising new area in cancer therapeutics. This review summarizes the current understanding of their mechanism of action, their state of clinical development, and possible mechanisms of resistance. RECENT FINDINGS: PARP inhibitors were predicted to cause leth...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855399/ https://ncbi.nlm.nih.gov/pubmed/20739886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e32833edbf8 |
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