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PARP Inhibitors: Science and Current Clinical Development

PURPOSE OF REVIEW: PARP inhibitors are a promising new area in cancer therapeutics. This review summarizes the current understanding of their mechanism of action, their state of clinical development, and possible mechanisms of resistance. RECENT FINDINGS: PARP inhibitors were predicted to cause leth...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Liu, Joyce F., Silver, Daniel P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855399/
https://ncbi.nlm.nih.gov/pubmed/20739886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e32833edbf8
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