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PARP Inhibitors: Science and Current Clinical Development

PURPOSE OF REVIEW: PARP inhibitors are a promising new area in cancer therapeutics. This review summarizes the current understanding of their mechanism of action, their state of clinical development, and possible mechanisms of resistance. RECENT FINDINGS: PARP inhibitors were predicted to cause leth...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Joyce F., Silver, Daniel P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855399/
https://ncbi.nlm.nih.gov/pubmed/20739886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e32833edbf8
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