Long-Term High-Altitude Hypoxia and Alpha Adrenoceptor-Dependent Pulmonary Arterial Contractions in Fetal and Adult Sheep

Autonomic innervation of the pulmonary vasculature triggers vasomotor contractility predominately through activation of alpha-adrenergic receptors (α-ARs) in the fetal circulation. Long-term hypoxia (LTH) modulates pulmonary vasoconstriction potentially through upregulation of α(1)-AR in the vascula...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Moretta, Dafne, Papamatheakis, Demosthenes G., Morris, Daniel P., Giri, Paresh C., Blood, Quintin, Murray, Samuel, Ramzy, Marian, Romero, Monica, Vemulakonda, Srilakshmi, Lauw, Sidney, Longo, Lawrence D., Zhang, Lubo, Wilson, Sean M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723549/
https://ncbi.nlm.nih.gov/pubmed/31555139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01032
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