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Depolarization-dependent contraction increase after birth and preservation following long-term hypoxia in sheep pulmonary arteries

Membrane depolarization is critical to pulmonary arterial (PA) contraction. Both L-type Ca(2+) channels (Ca(L)) and Rho-kinase are important signaling components of this process and mitochondrial and non-mitochondrial generated superoxides can be part of the signaling process. Maturation and long-te...

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Bibliographic Details
Main Authors: Papamatheakis, Demosthenes G., Patel, Jay J., Blood, Quintin, Merritt, Travis T., Longo, Lawrence D., Wilson, Sean M.
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342748/
https://ncbi.nlm.nih.gov/pubmed/22558519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.94832
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