Effect of chronic perinatal hypoxia on the role of rho-kinase in pulmonary artery contraction in newborn lambs

Exposure to chronic hypoxia during gestation predisposes infants to neonatal pulmonary hypertension, but the underlying mechanisms remain unclear. Here, we test the hypothesis that moderate continuous hypoxia during gestation causes changes in the rho-kinase pathway that persist in the newborn perio...

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Главные авторы: Blood, Arlin B., Terry, Michael H., Merritt, Travis A., Papamatheakis, Demosthenes G., Blood, Quintin, Ross, Jonathon M., Power, Gordon G., Longo, Lawrence D., Wilson, Sean M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
Предметы:
Cardiovascular and Renal Integration
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543659/
https://ncbi.nlm.nih.gov/pubmed/23152110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00126.2012
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