Effect of chronic perinatal hypoxia on the role of rho-kinase in pulmonary artery contraction in newborn lambs

Exposure to chronic hypoxia during gestation predisposes infants to neonatal pulmonary hypertension, but the underlying mechanisms remain unclear. Here, we test the hypothesis that moderate continuous hypoxia during gestation causes changes in the rho-kinase pathway that persist in the newborn perio...

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Hlavní autoři: Blood, Arlin B., Terry, Michael H., Merritt, Travis A., Papamatheakis, Demosthenes G., Blood, Quintin, Ross, Jonathon M., Power, Gordon G., Longo, Lawrence D., Wilson, Sean M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Cardiovascular and Renal Integration
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543659/
https://ncbi.nlm.nih.gov/pubmed/23152110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00126.2012
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