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C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly
Ragulator is a pentamer composed of p18, MP1, p14, C7orf59, and hepatitis B virus X‐interacting protein (HBXIP; LAMTOR 1—5) which acts as a lysosomal scaffold of the Rag GTPases in the amino acid sensitive branch of TORC1 signaling. Here, we present the crystal structure of human HBXIP‐C7orf59 dimer...
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| Publicado no: | FEBS Open Bio |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722880/ https://ncbi.nlm.nih.gov/pubmed/31314152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12700 |
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