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Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization

Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism, antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 C57BL/6 knockout mice (THOP1(−/−)) is described showing that they are viable, have estrus cycle, fertility, and a number of puppies...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biomolecules
Main Authors: dos Santos, Nilton B., Franco, Roseane D., Camarini, Rosana, Munhoz, Carolina D., Eichler, Rosangela A. S., Gewehr, Mayara C. F., Reckziegel, Patricia, Llanos, Ricardo P., Dale, Camila S., da Silva, Victoria R. O., Borges, Vanessa F., Lima, Braulio H. F., Cunha, Fernando Q., Visniauskas, Bruna, Chagas, Jair R., Tufik, Sergio, Peres, Fernanda F., Abilio, Vanessa C., Florio, Jorge C., Iwai, Leo K., Rioli, Vanessa, Presoto, Benedito C., Guimaraes, Alessander O., Pesquero, Joao B., Bader, Michael, Castro, Leandro M., Ferro, Emer S.
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722639/
https://ncbi.nlm.nih.gov/pubmed/31431000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9080382
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