The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity

Thimet oligopeptidase (EC 3.4.24.15; EP24.15; THOP1) is a potential therapeutic target, as it plays key biological functions in processing biologically functional peptides. The structural conformation of THOP1 provides a unique restriction regarding substrate size, in that it only hydrolyzes peptide...

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Publicat a:Biomolecules
Autors principals: Gewehr, Mayara C. F., Teixeira, Alexandre A. S., Santos, Bruna A. C., Biondo, Luana A., Gozzo, Fábio C., Cordibello, Amanda M., Eichler, Rosangela A. S., Reckziegel, Patrícia, Da Silva, Renée N. O., Dos Santos, Nilton B., Camara, Niels O. S., Castoldi, Angela, Barreto-Chaves, Maria L. M., Dale, Camila S., Senger, Nathalia, Lima, Joanna D. C. C., Seelaender, Marilia C. L., Inada, Aline C., Akamine, Eliana H., Castro, Leandro M., Rodrigues, Alice C., Rosa Neto, José C., Ferro, Emer S.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072564/
https://ncbi.nlm.nih.gov/pubmed/32079362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020321
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