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Optimizing Modified mRNA In Vitro Synthesis Protocol for Heart Gene Therapy
Synthetic modified RNA (modRNA) is a novel vector for gene transfer to the heart and other organs. modRNA can mediate strong, transient protein expression with minimal induction of the innate immune response and risk for genome integration. modRNA is already being used in several human clinical tria...
Tallennettuna:
| Julkaisussa: | Mol Ther Methods Clin Dev |
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| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Gene & Cell Therapy
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722299/ https://ncbi.nlm.nih.gov/pubmed/31508439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.07.006 |
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