Therapeutic Delivery of Pip4k2c‐Modified mRNA Attenuates Cardiac Hypertrophy and Fibrosis in the Failing Heart

Heart failure (HF) remains a major cause of morbidity and mortality worldwide. One of the risk factors for HF is cardiac hypertrophy (CH), which is frequently accompanied by cardiac fibrosis (CF). CH and CF are controlled by master regulators mTORC1 and TGF‐β, respectively. Type‐2‐phosphatidylinosit...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Adv Sci (Weinh)
मुख्य लेखकों: Magadum, Ajit, Singh, Neha, Kurian, Ann Anu, Sharkar, Mohammad Tofael Kabir, Sultana, Nishat, Chepurko, Elena, Kaur, Keerat, Żak, Magdalena M., Hadas, Yoav, Lebeche, Djamel, Sahoo, Susmita, Hajjar, Roger, Zangi, Lior
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2021
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132051/
https://ncbi.nlm.nih.gov/pubmed/34026458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202004661
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