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Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line

Nucleoporins have been reported to regulate pluripotent biology, but how they do so remains partially characterized. This study examined the effects of nup155 gene disruption on mouse embryonic stem cells to gain insights into possible mechanisms by which nucleoporins regulate pluripotency in a pro-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Preston, Claudia C., Storm, Emily C., Burdine, Ryan D., Bradley, Tyler A., Uttecht, Andrew D., Faustino, Randolph S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722237/
https://ncbi.nlm.nih.gov/pubmed/31481660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49147-4
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