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NUP155 insufficiency recalibrates a pluripotent transcriptome with network remodeling of a cardiogenic signaling module

BACKGROUND: Atrial fibrillation is a cardiac disease driven by numerous idiopathic etiologies. NUP155 is a nuclear pore complex protein that has been identified as a clinical driver of atrial fibrillation, yet the precise mechanism is unknown. The present study employs a systems biology algorithm to...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Preston, Claudia C., Wyles, Saranya P., Reyes, Santiago, Storm, Emily C., Eckloff, Bruce W., Faustino, Randolph S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977756/
https://ncbi.nlm.nih.gov/pubmed/29848314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0590-x
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