Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways That Regulate Cardiac Metabolism and Cell Fate in Newborn Rat Hearts

Background: Children born to diabetic or obese mothers have a higher risk of heart disease at birth and later in life. Using chromatin immunoprecipitation sequencing, we previously demonstrated that late-gestation diabetes, maternal high fat (HF) diet, and the combination causes distinct fuel-mediat...

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Publicado no:Front Endocrinol (Lausanne)
Main Authors: Preston, Claudia C., Larsen, Tricia D., Eclov, Julie A., Louwagie, Eli J., Gandy, Tyler C. T., Faustino, Randolph S., Baack, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527411/
https://ncbi.nlm.nih.gov/pubmed/33042024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.570846
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