Diabetic Pregnancy and Maternal High-Fat Diet Impair Mitochondrial Dynamism in the Developing Fetal Rat Heart by Sex-Specific Mechanisms

Infants born to diabetic or obese mothers are at greater risk of heart disease at birth and throughout life, but prevention is hindered because underlying mechanisms remain poorly understood. Using a rat model, we showed that prenatal exposure to maternal diabetes and a high-fat diet caused diastoli...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Larsen, Tricia D., Sabey, Kyle H., Knutson, Alexis J., Gandy, Tyler C. T., Louwagie, Eli J., Lauterboeck, Lothar, Mdaki, Kennedy S., Baack, Michelle L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627740/
https://ncbi.nlm.nih.gov/pubmed/31242551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123090
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