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The Impact of One Carbon Metabolism on Histone Methylation

The effect of one carbon metabolism on DNA methylation has been well described, bridging nutrition, metabolism, and epigenetics. This modification is mediated by the metabolite S-adenosyl methionine (SAM), which is also the methyl-donating substrate of histone methyltransferases. Therefore, SAM leve...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Serefidou, Magdalini, Venkatasubramani, Anuroop Venkateswaran, Imhof, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722216/
https://ncbi.nlm.nih.gov/pubmed/31555321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00764
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