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Measurement of Histone Methylation Dynamics by One-Carbon Metabolic Isotope Labeling and High-energy Collisional Dissociation Methylation Signature Ion Detection

Accumulating evidence suggests that cellular metabolites and nutrition levels control epigenetic modifications, including histone methylation. However, it is not currently possible to measure the metabolic control of histone methylation. Here we report a novel detection method to monitor methyl tran...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tang, Hui, Tian, Bing, Brasier, Allan R., Sowers, Lawrence C., Zhang, Kangling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987619/
https://ncbi.nlm.nih.gov/pubmed/27530234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31537
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