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Improving the Prediction of Local Drug Distribution Profiles in the Brain with a New 2D Mathematical Model

The development of drugs that target the brain is very challenging. A quantitative understanding is needed of the complex processes that govern the concentration–time profile of a drug (pharmacokinetics) within the brain. So far, there are no studies on predicting the drug concentration within the b...

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Detalhes bibliográficos
Publicado no:Bull Math Biol
Main Authors: Vendel, E., Rottschäfer, V., de Lange, E. C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722198/
https://ncbi.nlm.nih.gov/pubmed/30091104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-018-0469-4
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