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MHC-restricted Ag85B-specific CD8(+) T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice

Despite efforts to develop effective treatments and vaccines, Mycobacterium tuberculosis (Mtb), particularly pulmonary Mtb, continues to provide major health challenges worldwide. To improve immunization against the persistent health challenge of Mtb infection, we have studied the CD8(+) T cell resp...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Komine-Aizawa, Shihoko, Jiang, Jiansheng, Mizuno, Satoru, Hayakawa, Satoshi, Matsuo, Kazuhiro, Boyd, Lisa F., Margulies, David H., Honda, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722017/
https://ncbi.nlm.nih.gov/pubmed/31135967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201847988
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