Immunogenicity and Protective Efficacy against Murine Tuberculosis of a Prime-Boost Regimen with BCG and a DNA Vaccine Expressing ESAT-6 and Ag85A Fusion Protein

Heterologous prime-boost regimens utilizing BCG as a prime vaccine probably represent the best hope for the development of novel tuberculosis (TB) vaccines. In this study, we examined the immunogenicity and protective efficacy of DNA vaccine (pcD685A) expressing the fusion protein of Ag85A and ESAT-...

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Main Authors: Lu, Jia, Wang, Chun, Zhou, Zhiguang, Zhang, Ying, Cao, Tingting, Shi, Chunwei, Chen, Zhenhua, Chen, Lingxia, Cai, Changxue, Fan, Xionglin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065234/
https://ncbi.nlm.nih.gov/pubmed/21461375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/617892
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