The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe–2S cluster

Iron–sulfur clusters are protein cofactors with an ancient evolutionary origin. These clusters are best known for their roles in redox proteins such as ferredoxins, but some iron–sulfur clusters have nonredox roles in the active sites of enzymes. Such clusters are often prone to oxidative degradatio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bashiri, Ghader, Grove, Tyler L., Hegde, Subray S., Lagautriere, Thomas, Gerfen, Gary J., Almo, Steven C., Squire, Christopher J., Blanchard, John S., Baker, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721945/
https://ncbi.nlm.nih.gov/pubmed/31315931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009498
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