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Adaptive Responses as Mechanisms of Resistance to BRAF Inhibitors in Melanoma

The introduction of v-raf murine sarcoma viral oncogene homolog B (BRAF) inhibitors in melanoma patients with BRAF (V600E) mutations has demonstrated significant clinical benefits. However, rarely do tumours regress completely. Frequently, the reason for this is that therapies targeting specific onc...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Saei, Azad, Eichhorn, Pieter Johan Adam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721815/
https://ncbi.nlm.nih.gov/pubmed/31416288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081176
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