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Ubiquitination and adaptive responses to BRAF inhibitors in Melanoma

Response to targeted therapies is limited by the activation or inhibition of feedback loops. Here we report the ubiquitin specific peptidase 28/F-box WD repeat-containing protein 7 (USP28/FBW7) complex functions as a negative regulator of mitogen-activated protein kinase (MAPK) pathway by targeting...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Saei, Azad, Eichhorn, Pieter Johan Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154850/
https://ncbi.nlm.nih.gov/pubmed/30263945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1497862
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