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Overcharging Effect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates

Peptide-based small molecule drug conjugates for targeted tumor therapy are currently in the focus of intensive research. Anthracyclines, like daunomycin, are commonly used anticancer drug molecules and are also often applied in peptide-drug conjugates. However, lability of the O-glycosidic bond dur...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Pethő, Lilla, Mező, Gábor, Schlosser, Gitta
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720970/
https://ncbi.nlm.nih.gov/pubmed/31426442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24162981
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